Lancaster pa dating herpes
Episodic treatment of recurrent genital herpes is of questionable benefit, but it may be helpful in appropriately selected patients.
There is little evidence indicating benefit from treatment of recurrent orolabial herpes, which tends to be mild and infrequent.
Differences in shedding rates between genders have not been identified.
Women with established genital HSV-2 infection have asymptomatic shedding 1 to 5 percent of days,1 and many patients, especially those with recent primary infection or coinfection with HIV, shed virus even more frequently.1617 As many as 90 percent of those infected are unaware that they have herpes infection and may unknowingly shed virus and transmit infection.15Antiviral therapy is recommended for an initial genital herpes outbreak, especially if the patient has systemic symptoms or is immunocompromised.2 Oral acyclovir is effective in reducing symptoms1 .
The gold standard of diagnosis is viral isolation by tissue culture,1 although this process can take as long as four to five days, and the sensitivity rate is only 70 to 80 percent.
Retrograde transport through adjacent neural tissue to sensory ganglia leads to lifelong latent infection.1 Reactivation of the virus is triggered by local or systemic stimuli such as immunodeficiency, trauma, fever, menstruation, ultraviolet (UV) light and sexual intercourse.1-3 Although emotional stress is assumed to trigger HSV recurrence, recent research fails to show a definite causative role.4 Once reactivated, the virus is transported by the neuron back to the epithelium, where more replication occurs, and another outbreak ensues.
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New antiviral medications have expanded treatment options for the two most common cutaneous manifestations, orolabial and genital herpes. Acyclovir therapy remains an effective and. DAVID H. EMMERT, M. D. Lancaster General Hospital, Lancaster, Pennsylvania. Am Fam Physician. 2000 Mar 15;6161697-1704.… continue reading »
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